What is common variable immune deficiency

Last Updated on March 14, 2023 by Dr. Saqib Mueed

Common Variable Immune Deficiency (CVID) is a type of primary immunodeficiency, which is usually the result of a breakdown of the immune framework. The main reason of this disorder is the change in DNA structure due to mutations. [1]vol30issue1_2.pdf (jiaci.org)

Signs and Symptoms 

Clinical courses and CVID explanations generally range from simple to extreme.  For example, some patients lack 3 main types of immunoglobulins immunoglobulin N (IgA), and immunoglobulin M (IgM), while others have only one or two.

CVIDs result of the absence of antibodies that are commonly used to counter attacks of antigens so the body is will more prone for infections.

Frequent bacterial contamination affects the lower and upper respiratory tract, for example, Occasional lung pollution can lead to persistent lung diseases and effective discomfort.

Gastrointestinal complications: Some patients report abdominal cramps, swelling, illness, heaving, intestinal loose, and weight loss. 

People with CVID may likewise encounter frequent or associated contamination (giardiasis) of the digestive system, which is brought about by parasites  called Giridialamblia.

Similarly, people with CVID a tendency to expand on certain bacterial gastrointestinal infections (eg, campylobacter) that can cause side effects, such as those associated with giardiasis.[2]Common Variable Immunodeficiency – an overview | ScienceDirect Topics 

Infected population of common variable immune deficiency

The cases of CVID’s lead is close to 1 in every 30,000 people. 

Food for common variable immune deficiency

Nourishing foods that are high in nutrients K (which affect the bloodstream, for example, broccoli, spinach, kale, and other green vegetables, liver, grapefruit and grapefruit extract, and green tea, either in solid amounts) Should be eaten or kept away from. [3]Primary Immunodeficiency Diseases and Gastrointestinal Distress: Coping Strategies and Dietary Experiences to Relieve Symptoms (nih.gov)

Treatment options

The latest anti-coagulants, for example, apixaban, rivaroxaban, adoxaban, and debigatran, have some preferences for heparin or warfarin. Like warfarin, these medicines can also be taken by mouth, yet there is no need for a part modification and test to screen for the degree of anticoagulation. [4]A review on guidelines for management and treatment of common variable immunodeficiency – PubMed (nih.gov)

Reviewed by:
Dr. Shafaat Yar Khan  (Ph.D.) 
Medical University of Vienna, Austria 
Present: University of Sargodha, Pakistan

Our reviewers’ details, Click Here

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